Ferroptosis: Under pressure!

Adam Wahida; Marcus Conrad

doi:10.1016/j.cub.2023.03.009

Ferroptosis: Under pressure!

Curr Biol. 2023 Apr 10;33(7):R269-R272. doi: 10.1016/j.cub.2023.03.009.

Authors

Adam Wahida¹, Marcus Conrad²

Affiliations

¹ Institute of Metabolism and Cell Death, Helmholtz Center Munich, Neuherberg, Germany; Division of Gynecological Oncology, National Center of Tumor Diseases (NCT), and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: adamwahida@gmail.com.
² Institute of Metabolism and Cell Death, Helmholtz Center Munich, Neuherberg, Germany.

PMID: 37040709
DOI: 10.1016/j.cub.2023.03.009

Abstract

Ferroptosis is a disease-relevant and pervasive form of cell death triggered by iron-dependent lipid peroxidation and resulting in membrane rupture. A new study addresses how tension-sensing channels can balance and modulate membrane tension in the context of ferroptotic cell death.

Publication types

Comment

MeSH terms

Cell Death
Ferroptosis* / physiology
Iron / metabolism
Lipid Peroxidation

Substances

Iron