Neuroscience: Moving thoughts control insulin release

Curr Biol. 2023 Apr 10;33(7):R274-R276. doi: 10.1016/j.cub.2023.02.054.


Insulin release has mostly been studied in the context of metabolic signals. An electrophysiology approach in Drosophila now reveals regulation of insulin-producing cell activity by neuronal circuits controlling locomotion. Even without actual movement, activating these circuits is sufficient to inhibit neuropeptide release.

Publication types

  • Comment

MeSH terms

  • Animals
  • Drosophila / physiology
  • Drosophila Proteins* / metabolism
  • Insulin* / metabolism
  • Locomotion / physiology
  • Neurons / metabolism


  • Insulin
  • Drosophila Proteins