COVID-19 in patients with chronic kidney disease: a 2-year study of incidence and mortality in relation to the variants of concern waves in Brazil

Trans R Soc Trop Med Hyg. 2023 Aug 3;117(8):606-608. doi: 10.1093/trstmh/trad019.

Abstract

Background: Chronic kidney disease (CKD) is a risk factor for severe coronavirus disease (COVID-19). In Brazil, the disease is the 10th highest cause of death. We evaluated the epidemiological impact of COVID-19 in CDK and non-CDK patients.

Methods: Positive patients for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from 2020 to 2022 were classified according to the severity of COVID-19 and the numbers of cases and deaths were correlated to each wave of SARS-CoV-2 variants in Brazil.

Results: We compared all variables, and our data show that CDK significantly increased the mortality rate among patients, especially before COVID-19 vaccination, in comparison with non-CKD patients.

Conclusions: CKD patients had a significantly increased mortality rate compared with non-CKD.

Keywords: COVID-19; COVID-19 vaccines; SARS-CoV-2; chronic kidney disease; mortality; variants of concern.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brazil / epidemiology
  • COVID-19 Vaccines
  • COVID-19* / epidemiology
  • Humans
  • Incidence
  • Renal Insufficiency, Chronic* / epidemiology
  • SARS-CoV-2

Substances

  • COVID-19 Vaccines

Supplementary concepts

  • SARS-CoV-2 variants