Evolving Science on Cardiovascular Disease Among Hispanic/Latino Adults: JACC International

J Am Coll Cardiol. 2023 Apr 18;81(15):1505-1520. doi: 10.1016/j.jacc.2023.02.023.


The landmark, multicenter HCHS/SOL (Hispanic Community Health Study/Study of Latinos) is the largest, most comprehensive, longitudinal community-based cohort study to date of diverse Hispanic/Latino persons in the United States. The HCHS/SOL aimed to address the dearth of comprehensive data on risk factors for cardiovascular disease (CVD) and other chronic diseases in this population and has expanded considerably in scope since its inception. This paper describes the aims/objectives and data collection of the HCHS/SOL and its ancillary studies to date and highlights the critical and sizable contributions made by the study to understanding the prevalence of and changes in CVD risk/protective factors and the burden of CVD and related chronic conditions among adults of diverse Hispanic/Latino backgrounds. The continued follow-up of this cohort will allow in-depth investigations on cardiovascular and pulmonary outcomes in this population, and data from the ongoing ancillary studies will facilitate generation of new hypotheses and study questions.

Keywords: Hispanic/Latino; cardiovascular disease; cohort study; study design.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Cardiovascular Diseases* / epidemiology
  • Cohort Studies
  • Heart Disease Risk Factors*
  • Hispanic or Latino* / statistics & numerical data
  • Humans
  • Multicenter Studies as Topic
  • Prevalence
  • Risk Factors
  • United States / epidemiology