Conflict of Interest Disclosures: Dr Emanuel reported personal fees from UnitedHealth Group, Blue Cross Blue Shield, CBI/Informa, RISE Health, Galien Foundation, Rightway, Signature Healthcare Foundation, Healthcare Leaders of New York, MedImpact, Princeton University, Philadelphia Committee on Foreign Relations, Yale University, Hartford Medical Society, Global Innovation Forum, the Hawaii Medical Service Association and Queen’s Health System, Macalester College, Advocate Aurora Health Summit, DPharm, University of Pittsburgh Shadyside Medical Center, University of California, San Francisco Department of Urology, Advocate Aurora Health, Cain Brothers, and Bowdoin College; serving as an uncompensated speaker, panelist, or moderator for Center for Global Development, American Academy of Arts and Sciences, University of California, San Francisco, World Affairs, Unite Us, University of Pennsylvania Engaging Minds, Vagelos College of Physicians and Surgeons, United Nations Educational, Scientific and Cultural Organization Global Conference, School of Pharmaceutical and Biotech Business, National Institutes of Health Demystifying Medicine Series, American Society of Preventive Oncology 45th Annual Meeting, Blue Cross Blue Shield National Customer Advisory Council, University of Pennsylvania Cellicon Valley 2021, Independent Health and Aged Care Pricing Authority Activity Based Funding Conference, University of Pennsylvania Leonard Davis Institute of Health Economics, Penn Medicine Alumni Weekend, National Health Equity Summit, Galien Foundation, Temple Sholom of Chicago, Perry World House Graduate Association, the Italian Medicine Agency, Penn Rising Scholar Success Academy, Syllable and Oak Portico, Rainbow PUSH Coalition, Infectious Diseases Society of America, VinFuture, Leonard David Institute, Brown University, Organisation for Economic Co-operation and Development, 21st Population Health Colloquium, VillageMD, University of Pennsylvania College of Liberal and Professional Studies, University of Sydney, Tel Aviv University, American Philosophical Society, Health Action Alliance, Yale University, Association of Bioethics Program Directors Spring Meeting, Icahn School of Medicine at Mount Sinai, Abramson Cancer Center, University of Minnesota, Institute for Peace and Security Studies Addis Conference, Faith Health Alliance, The Wharton School at the University of Pennsylvania, Oak CEO Summit, Centers for Disease Control and Prevention, American Academy of Political and Social Science, Primary Care Transformation, 16th World Congress of Bioethics, Blue Cross Blue Shield Alliance for Health Research, White House Cancer Moonshot, BC Philadelphia, American Society of Clinical Oncology Quality Care Symposium, and Brookings Institution; serving on the board of advisors of Notable, external advisory board of VillageMD, advisory board of Health Innovation Exchange, internal advisory board of Colton Center for Autoimmunity, advisory board of JSL Health Fund, expert advisory board of the World Health Organization COVID-19 Ethics & Governance Working Group, and advisory board of President Biden’s Transition COVID-19 Committee; and serving as special advisor to the World Health Organization director general, member of the advisory board of the Peterson Foundation, advisor for Clarify Health, unpaid board member for Oncology Analytics, founding member of COVID-19 Recovery LLC, founding partner of Embedded LLC, venture partner of Oak HC/FT, and a member of the board of advisors for Cellares. Dr W. Richards reported grants from COMPASS Pathways during the conduct of the study and stock in COMPASS Pathways outside the submitted work. Dr Thambi reported nonfinancial support from COMPASS Pathways and grants from Shady Grove Medical Center Foundation during the conduct of the study, as well as stock in Sunstone Therapies outside the submitted work. No other disclosures were reported.