Clinical and imaging features of eight cases of Ewing sarcoma of the jaw

Hua Xi Kou Qiang Yi Xue Za Zhi. 2023 Apr 1;41(2):185-189. doi: 10.7518/hxkq.2023.2022325.
[Article in English, Chinese]

Abstract

Objectives: This study investigate the clinical and imaging features of Ewing sarcoma (ES) of the jaw.

Methods: Eight cases of pathologically diagnosed ES of the jaw from January 2010 to June 2022 were included in the study. Clinical and radiological features were retrospectively analyzed.

Results: Among the eight cases, the mean age at onset was 29.4 years, and the male to female ratio was 7∶1. The predilecting site was the posterior part of mandible, accounting for 75% of the cases. The lesions often exhibited early numbness of the lower lip and lymphadenopathy. The main radiographic manifestation of mandibular lesions was ill-defined radiolucency, mixed with fibrous or brush-like tumor matrix, and soft tissue mass. The maxillary ES lesions mainly presented as lytic bone destruction accompanied by adjacent soft tissue mass. Periosteal ossification was rarely seen.

Conclusions: The clinical and imaging characteristics of ES in the jaw are helpful for its diagnosis.

目的: 探讨颌骨尤文肉瘤的临床表现及CT影像学特征。方法: 回顾性分析2010年1月—2022年6月经病理证实的8例颌骨尤文肉瘤的临床表现及CT影像学特征。结果: 8例颌骨尤文肉瘤病例的发病平均年龄为29.4岁,男女比例为7∶1,发病部位下颌骨后部多见(75%),早期多数有下唇麻木及淋巴结肿大表现。下颌骨尤文肉瘤影像学表现为颌骨内混杂低密度骨质破坏伴软组织肿块形成,纤维索条状及毛刷状瘤骨为其特征型影像学表现。上颌骨尤文肉瘤主要变现为溶蚀状骨质破坏,伴软组织肿块形成。骨膜成骨少见。结论: 颌骨尤文肉瘤具有一定的临床及影像学特征,这有助于其影像诊断。.

Keywords: Ewing sarcoma; clinical manifestation; imaging features; jaw.

MeSH terms

  • Bone Neoplasms*
  • Female
  • Humans
  • Lip
  • Male
  • Mandible / pathology
  • Radiography
  • Retrospective Studies
  • Sarcoma, Ewing* / diagnostic imaging
  • Sarcoma, Ewing* / pathology

Grants and funding

[基金项目] 江苏省南京市医学科技发展项目(YKK15116);江苏省自然科学基金面上项目(BK20150089);南京市医学科技发展资金项目(QRX17079)