Dietary carbohydrates in the management of epilepsy

Curr Opin Clin Nutr Metab Care. 2023 Jul 1;26(4):377-381. doi: 10.1097/MCO.0000000000000938. Epub 2023 Apr 14.

Abstract

Purpose of review: The role of dietary carbohydrates in the management of epilepsy is intrinsically linked to the ketogenic diet. The ketogenic diet has been in use for well over a century now. There have been numerous adaptations to the diet. It is crucial to understand the indications and role of the ketogenic diet in the management of epilepsy.

Recent findings: There have been new studies that have looked at the role of ketogenic ratios in seizure control. In addition, there has been new evidence in the role of using the ketogenic diet therapy instead of antiseizure medications. These data highlight that the ketogenic diet should be tailored for patients and caregivers. When used appropriately, it can result in a significant improvement in seizure control as well as cognitive and developmental gains.

Summary: The ketogenic diet therapy has undergone numerous revisions and reiterations from its initial reported use in patients a century ago. This has enabled us to tailor the diet specific to each patient's underlying diagnosis.

Publication types

  • Review

MeSH terms

  • Diet, Ketogenic*
  • Dietary Carbohydrates
  • Epilepsy*
  • Humans
  • Ketone Bodies
  • Seizures
  • Treatment Outcome

Substances

  • Dietary Carbohydrates
  • Ketone Bodies