Wiad Lek. 2023;76(3):467-473. doi: 10.36740/WLek202303101.


Objective: The aim: To determine the role of infectious diseases as the cause of the Cervical, Ovarian and Breast hyperplasia in Ukraine.

Patients and methods: Materials and methods: We conducted a retrospective multicenter cohort study from January 1st, 2020 to December 31st, 2022. This study included patients aged 20-59 years with a diagnosis of hyperproliferative pathology of the women reproductive organs without atypia, who sought medical care for hyperplastic processes admitted to the 12 hospitals from 9 regions of Ukraine.

Results: Results: We had examined 4,713 women; out of which 81.1% met the clinical definition of female reproductive organs hyperplasia. Of all hyperplasia cases, most frequently recorded types were breast hyperplasia (41,7%), followed by cervical hyperplasia (31,1%) and ovarian hyperplasia (27,2%). History of Cervicitis (p<0.001), Vaginal cuff infection (p<0.001), Oophoritis (p<0.001), and Mastitis (p<0.001) were identified as independent risk factors of Cervical, Ovarian and Breast hyperplasia.

Conclusion: Conclusions: This study showed that surgical site infections after obstetric and gynecological operations are is the cause of Cervical, Ovarian and Breast hyperplasia. Therefore, early detection and treatment SSIs can reduce the risk of hyperplasia these organs.

Keywords: Ukraine; breast hyperplasia; cervical hyperplasia; ovarian hyperplasia; risk factors; surgical site infection.

Publication types

  • Multicenter Study

MeSH terms

  • Breast Neoplasms*
  • Cohort Studies
  • Female
  • Humans
  • Hyperplasia
  • Pregnancy
  • Risk Factors
  • Ukraine / epidemiology