Spontaneous regression of a choroidal melanoma

Arch Ophthalmol. 1986 May;104(5):732-4. doi: 10.1001/archopht.1986.01050170122036.


Although spontaneous regression of uveal malignant melanoma is rare, its occurrence is not uncommon in cutaneous melanomas. We report a 15-year follow-up of an enlarging posterior pigmented tumor. It initially appeared to spontaneously regress into a flat chorioretinal scar, but, ten years later, it grew markedly and the eye was enucleated. Histopathologic changes similar to those found in regressed cutaneous melanomas were located in the region of the chorioretinal scar.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Choroid / pathology
  • Choroid Neoplasms / pathology*
  • Humans
  • Male
  • Melanoma / pathology*
  • Neoplasm Recurrence, Local
  • Neoplasm Regression, Spontaneous*
  • Retina / pathology