Resolving a paradox between mouse and man: a genetic link between TLR7 and the pathogenesis of human lupus nephritis

Kidney Int. 2023 May;103(5):824-826. doi: 10.1016/j.kint.2023.01.019.

Authors

Shaun W Jackson¹, Brad H Rovin²

Affiliations

¹ Seattle Children's Research Institute, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA; Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA. Electronic address: shaun.jackson@seattlechildrens.org.
² Nephrology Division, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

PMID: 37085253
DOI: 10.1016/j.kint.2023.01.019

No abstract available

Keywords: antinuclear autoantibodies; autoreactive B cells; human genetics; lupus nephritis; toll-like receptors.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Antibodies, Antinuclear
Autoantibodies
Humans
Lupus Nephritis* / genetics
Lupus Nephritis* / pathology
Toll-Like Receptor 7* / genetics

Substances

Antibodies, Antinuclear
Autoantibodies
TLR7 protein, human
Toll-Like Receptor 7

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