Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review

Cureus. 2023 Mar 21;15(3):e36481. doi: 10.7759/cureus.36481. eCollection 2023 Mar.

Abstract

Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune condition with various triggers. Because of the lack of randomized controlled trials on LABD treatment, management options are mostly anecdotal. This paper provides a comprehensive review of treatment options from a literature review of reported treatments to arm clinicians with a guideline for the management of LABD in both pediatric and adult patients as well as those recalcitrant to first-line therapy (dapsone and steroids). We additionally illustrate an algorithm to use for the management of LABD to aid clinicians when faced with unique patient circumstances.

Keywords: autoimmune bullous dermatoses; chronic bullous disease of childhood; labd; linear iga bullous dermatosis; linear iga dermatosis.

Publication types

  • Review