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. 2023 Jul;210(1):54-63.
doi: 10.1097/JU.0000000000003492. Epub 2023 Apr 25.

Early Detection of Prostate Cancer: AUA/SUO Guideline Part II: Considerations for a Prostate Biopsy

John T Wei  1 , Daniel Barocas  2 , Sigrid Carlsson  3 , Fergus Coakley  4 , Scott Eggener  5 , Ruth Etzioni  6 , Samson W Fine  3 , Misop Han  7 , Sennett K Kim  8 , Erin Kirkby  8 , Badrinath R Konety  9 , Martin Miner  10 , Kelvin Moses  2 , Merel G Nissenberg  11 , Peter A Pinto  12 , Simpa S Salami  1 , Lesley Souter  13 , Ian M Thompson  14 , Daniel W Lin  15
Affiliations

Early Detection of Prostate Cancer: AUA/SUO Guideline Part II: Considerations for a Prostate Biopsy

John T Wei et al. J Urol. 2023 Jul.

Abstract

Purpose: The summary presented herein covers recommendations on the early detection of prostate cancer and provides a framework to facilitate clinical decision-making in the implementation of prostate cancer screening, biopsy, and follow-up. This is Part II of a two-part series focusing on initial and repeat biopsies, and biopsy technique. Please refer to Part I for discussion of initial prostate cancer screening recommendations.

Materials and methods: The systematic review utilized to inform this guideline was conducted by an independent methodological consultant. The systematic review was based on searches in Ovid MEDLINE and Embase and Cochrane Database of Systematic Reviews (January 1, 2000-November 21, 2022). Searches were supplemented by reviewing reference lists of relevant articles.

Results: The Early Detection of Prostate Cancer Panel developed evidence- and consensus-based guideline statements to provide guidance in prostate cancer screening, initial and repeat biopsies, and biopsy technique.

Conclusions: The evaluation of prostate cancer risk should be focused on the detection of clinically significant prostate cancer (Grade Group 2 or higher [GG2+]). The use of laboratory biomarkers, prostate MRI, and biopsy techniques described herein may improve detection and safety when a prostate biopsy is deemed necessary following prostate cancer screening.

Keywords: AIP; ASAP; HGPIN; MRI; PI-RADS; PSA; biomarkers; biopsy technique; early detection of prostate cancer; imaging; prostate cancer biopsy; prostate cancer screening; transperineal; transrectal.

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Figures

FIGURE 2:
FIGURE 2:
ELEVATED RISK EVALUATION
FIGURE 3:
FIGURE 3:
AFTER A NEGATIVE BIOPSY
See this image and copyright information in PMC

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