Granulomatosis with Polyangiitis Misdiagnosed as IgA Vasculitis in a Child

Sheida Amini; Mohsen Jari

doi:10.1155/2023/9950855

Granulomatosis with Polyangiitis Misdiagnosed as IgA Vasculitis in a Child

Case Rep Pediatr. 2023 Apr 17:2023:9950855. doi: 10.1155/2023/9950855. eCollection 2023.

Authors

Sheida Amini¹, Mohsen Jari²

Affiliations

¹ Department of Pediatric, Imam Hussein Children's Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
² Department of Pediatric Rheumatology, Imam Hussein Children's Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Background: Granulomatosis with polyangiitis (GPA) with early manifestations simulating IgA vasculitis is a very rare childhood systemic disease. Case Presentation. A 10-year-old boy presented initially with cutaneous, skeletal, and abdominal signs suggestive of IgA vasculitis. Over time, the worsening of skin ulcers, orchitis, and renal involvement led to the diagnosis of GPA according to cytoplasmic positive antineutrophil cytoplasmic antibodies and renal biopsy.

Conclusion: Clinicians should be awared of the diagnostic pitfalls when making a clinical diagnosis of IgA vasculitis in children older than 7 years.

Publication types

Case Reports