Prevention of subglottic stenosis in neonatal ventilation

Int J Pediatr Otorhinolaryngol. 1986 Feb;11(1):61-6. doi: 10.1016/s0165-5876(86)80028-3.


Mechanical ventilation of the newborn is now widely used in neonatal intensive care. The oro-tracheal route of intubation is simpler, but for long-term ventilation has been considered unstable. A method of fixation of oro-tracheal tubes is described which overcomes this instability. Five hundred consecutive ventilated infants were intubated by the oro-tracheal route and the tube was fixed by the method described. Of the 500 ventilated infants, 213 died without being extubated. Of the 287 survivors, 44 developed a degree of post-extubation stridor. No surviving infant developed clinical evidence of subglottic stenosis and in almost 200 postmortem examinations laryngeal narrowing was not identified. The method of oro-tracheal fixation described is stable and may reduce the incidence of subglottic stenosis.

MeSH terms

  • Beclomethasone / therapeutic use
  • Body Weight
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intubation, Intratracheal / adverse effects
  • Intubation, Intratracheal / methods*
  • Laryngostenosis / etiology
  • Laryngostenosis / prevention & control*
  • Respiration, Artificial / adverse effects
  • Respiration, Artificial / methods*
  • Respiratory Sounds / etiology


  • Beclomethasone