An Assessment of Current Clinician-Reported and Patient-Reported Outcome Measures for Alopecia Areata: A Scoping Review

J Invest Dermatol. 2023 Jul;143(7):1133-1137.e12. doi: 10.1016/j.jid.2023.02.020. Epub 2023 Apr 28.

Abstract

Although progress has been made in developing outcome measures for AA, the use of these measures remains unstandardized. A scoping review was conducted to identify the clinician-reported outcome measures (ClinROMs) and patient-reported outcome measures (PROMs) used in assessing and treating AA, the results of which revealed heterogeneity in AA outcome measures. Of 23 research studies ultimately included, only 2 ClinROMs were used by >15% of studies; likewise, of 110 clinical trials evaluated, numerous outcome instruments were used, but only one ClinROM was used by >5% of trials (Severity of Alopecia Tool). These results suggest the need for consensus and standardization in both research and trial settings.

Keywords: AA; COS; ClinROM; HRQoL; PROM; SALT; Severity of Alopecia Tool; alopecia areata; clinician-reported outcome measure; core outcomes set; health-related quality of life; patient-reported outcome measure.

Publication types

  • Review

MeSH terms

  • Alopecia / diagnosis
  • Alopecia / therapy
  • Alopecia Areata* / drug therapy
  • Alopecia Areata* / therapy
  • Humans
  • Outcome Assessment, Health Care
  • Patient Reported Outcome Measures
  • Psychometrics

Supplementary concepts

  • Diffuse alopecia