Pop-eye: an inherited Z-linked keratoglobus in the chicken

J Hered. 1986 Mar-Apr;77(2):123-5. doi: 10.1093/oxfordjournals.jhered.a110183.


A Z-linked recessive mutation in the domestic fowl is reported that results in a keratoglobus of both eyes. It does not appear to have any effect on the vision of affected individuals. The keratoglobus is not noticeable at hatching, but becomes obvious by 5-6 weeks of age. The mutant has been designated pop-eye, gene symbol pop. Initial studies suggest linkage with the late feathering (K) locus, and with the NM 7092 t (Z;1) translocation, which had previously been shown to be closely linked with Z-linked silver (S). There appear to be no other detrimental effects associated with this mutant. Preliminary analysis of T3 and T4 thyroid hormone levels do not indicate any thyroid malfunction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chickens / genetics*
  • Cornea / abnormalities*
  • Crosses, Genetic
  • Female
  • Genetic Linkage
  • Male
  • Phenotype
  • Poultry Diseases / genetics*
  • Sex Chromosomes