Unusual Instance of Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Confined to a Colonic Polyp

Amy Kiamos; Reeba Omman; J R Quan

doi:10.7759/cureus.36791

Unusual Instance of Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Confined to a Colonic Polyp

Cureus. 2023 Mar 28;15(3):e36791. doi: 10.7759/cureus.36791. eCollection 2023 Mar.

Authors

Amy Kiamos¹, Reeba Omman², J R Quan³

Affiliations

¹ Internal Medicine, University of Florida College of Medicine, Jacksonville, USA.
² Pathology, University of Florida College of Medicine, Jacksonville, USA.
³ Oncology, University of Florida College of Medicine, Jacksonville, USA.

Abstract

Extranodal marginal zone lymphoma (EMZL) of mucosa-associated lymphoid tissue (MALT) commonly affects the gastrointestinal (GI) tract but rarely occurs within the colon. Colonic EMZL is a rare diagnosis accounting for 2.5% of EMZL and less than 0.5% of colon cancers. We present a unique case of asymptomatic colonic EMZL diagnosed on a routine surveillance colonoscopy. The lymphoma was confined to a single colonic polyp presenting endoscopically as a sessile polypoid lesion at the recto-sigmoid junction. The patient was successfully treated with polypectomy with no recurrence of the disease.

Keywords: colon cancer and colon polyps; extranodal lymphoma of the colon; extranodal malt lymphoma; extranodal marginal zone malt lymphoma; marginal zone lymphoma (mzl); mucosa-associated lymphoid tissue (malt) lymphoma.

Publication types

Case Reports