Synthesis of Tetracyclic C2-Symmetric Ketiminium Salts and Evaluation as Catalysts for Epoxidation

G Sudhakar Reddy; E J Corey

doi:10.1021/acs.orglett.3c01123

Synthesis of Tetracyclic C₂-Symmetric Ketiminium Salts and Evaluation as Catalysts for Epoxidation

Org Lett. 2023 May 19;25(19):3539-3542. doi: 10.1021/acs.orglett.3c01123. Epub 2023 May 4.

Authors

G Sudhakar Reddy¹, E J Corey¹

Affiliation

¹ Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.

PMID: 37140440
DOI: 10.1021/acs.orglett.3c01123

Abstract

Short synthetic routes to the nonplanar tetracyclic ketiminium salt A and two close analogs are described. These are helical nonplanar structures as shown by X-ray crystallography.