Isolated gastric involvement of recurrent Hodgkin lymphoma: a case report and review of the literature

J Med Case Rep. 2023 May 5;17(1):178. doi: 10.1186/s13256-023-03918-w.


Background: Although the gastrointestinal tract is one of the most common sites for extranodal lymphoma, gastrointestinal lymphoma is a rare disease that is almost exclusively non-Hodgkin lymphoma.

Case presentation: We present a rare condition of Hodgkin lymphoma relapse after 12 years as isolated gastric involvement caused massive gastrointestinal bleeding in a 34-year-old Iranian woman. According to the result of the upper endoscopy, laparotomy was performed, and a large mass in the upper part of the fundus, alongside the esophagogastric junction, was seen, so gastrectomy was performed.

Conclusion: All symptoms and paraclinical findings for gastrointestinal Hodgkin lymphoma are nonspecific. Therefore, the preoperative diagnosis is challenging. It seems that surgery is a suitable diagnostic and therapeutic method in this field.

Keywords: Gastrointestinal Hodgkin lymphoma; Gastrointestinal bleeding; Hodgkin lymphoma.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adult
  • Female
  • Gastrointestinal Neoplasms* / pathology
  • Hodgkin Disease* / complications
  • Hodgkin Disease* / diagnosis
  • Humans
  • Iran
  • Lymphoma*
  • Lymphoma, Non-Hodgkin* / complications
  • Lymphoma, Non-Hodgkin* / diagnosis
  • Neoplasm Recurrence, Local