Perspectives on validation of clinical predictive algorithms

NPJ Digit Med. 2023 May 6;6(1):86. doi: 10.1038/s41746-023-00832-9.


The generalizability of predictive algorithms is of key relevance to application in clinical practice. We provide an overview of three types of generalizability, based on existing literature: temporal, geographical, and domain generalizability. These generalizability types are linked to their associated goals, methodology, and stakeholders.