Current status of Cancer Nanotheranostics: Emerging strategies for cancer management

Nanotheranostics. 2023 May 1;7(4):368-379. doi: 10.7150/ntno.82263. eCollection 2023.


Cancer diagnosis and management have been a slow-evolving area in medical science. Conventional therapies have by far proved to have various limitations. Also, the concept of immunotherapy which was thought to revolutionize the management of cancer has presented its range of drawbacks. To overcome these limitations nanoparticulate-derived diagnostic and therapeutic strategies are emerging. These nanomaterials are to be explored as they serve as a prospect for cancer theranostics. Nanoparticles have a significant yet unclear role in screening as well as therapy of cancer. However, nanogels and Photodynamic therapy is one such approach to be developed in cancer theranostics. Photoactive cancer theranostics is a vivid area that might prove to help manage cancer. Also, the utilization of the quantum dots as a diagnostic tool and to selectively kill cancer cells, especially in CNS tumors. Additionally, the redox-sensitive micelles targeting the tumor microenvironment of the cancer are also an important theranostic tool. This review focuses on exploring various agents that are currently being studied or can further be studied as cancer theranostics.

Keywords: cancer; nanoparticles; photodynamic therapy; photosensitive agents; photothermal therapy; theranostics.

Publication types

  • Review

MeSH terms

  • Humans
  • Nanoparticles* / therapeutic use
  • Nanostructures* / therapeutic use
  • Neoplasms* / drug therapy
  • Photochemotherapy* / methods
  • Theranostic Nanomedicine / methods
  • Tumor Microenvironment