Hospital-at-home care for immunodeficient patients with COVID-19: Approach to persistent COVID-19 infection

Yuki Miyamoto; Yasufumi Matsumura; Shougen Sumiyoshi; Yoshiki Morikami; Miki Nagao

doi:10.1002/ccr3.7294

Hospital-at-home care for immunodeficient patients with COVID-19: Approach to persistent COVID-19 infection

Clin Case Rep. 2023 May 4;11(5):e7294. doi: 10.1002/ccr3.7294. eCollection 2023 May.

Authors

Yuki Miyamoto^{1

2}, Yasufumi Matsumura³, Shougen Sumiyoshi⁴, Yoshiki Morikami², Miki Nagao³

Affiliations

¹ Department of Emergency Medicine Kyoto Prefectural University of Medicine Kyoto Japan.
² Yoshiki Home Care Clinic Kyoto Japan.
³ Department of Clinical Laboratory Medicine Kyoto University Graduate School of Medicine Kyoto Japan.
⁴ Department of Infectious Diseases Kyoto City Hospital Kyoto Japan.

Abstract

Key clinical message: Patients with COVID-19 who have undergone B-cell depletion therapy could have prolonged SARS-CoV-2 infection; therefore, even in the hospital-at-home setting, primary care physicians should carefully consider the treatment regimen and the timing of ending isolations in such cases, and should not hesitate to consult with infectious disease specialists if necessary.

Abstract: We presented the first reported case of hospital-at-home care for a patient with persistent COVID-19 who had undergone B-cell depletion therapy. He received hospital-at-home care, including two courses of remdesivir; however, he ultimately failed to recover and was transferred to the hospital.

Keywords: COVID‐19; home care medicine; hospital‐at‐home; immunodeficiency; primary care.

Publication types

Case Reports