1 Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
2 IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
3 Laboratory of Biological Structure Mechanics (LaBS), Department of Chemistry, Materials and Chemical Engineering 'Giulio Natta', Politecnico di Milano, Milan, Italy.
4 Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210th St, Bronx, NY, 10467, USA.