Malignant Germ Cell Tumors of the Ovary: Clinical and Imaging Features

Radiol Clin North Am. 2023 Jul;61(4):579-594. doi: 10.1016/j.rcl.2023.02.004. Epub 2023 Apr 3.


Ovarian malignant germ cell tumors are a diverse set of masses originating from the primitive gonadal germ cells, often in young females. They have useful imaging and clinical features, including serum tumor marker elevation, that may aid the radiologist at the time of diagnosis, and also during follow-up. Accurate and timely diagnosis is essential, as standard-of-care therapies lead to a high rate of cancer remission.

Keywords: CT; Dysgerminoma; Immature teratoma; MR; Ovarian malignant germ cell tumor; Ultrasound; Yolk sac tumor.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor
  • Female
  • Humans
  • Neoplasms, Germ Cell and Embryonal* / diagnostic imaging
  • Ovarian Neoplasms* / diagnostic imaging
  • Ovarian Neoplasms* / pathology


  • Biomarkers, Tumor