Malignant Germ Cell Tumors of the Ovary: Clinical and Imaging Features

Douglas Rogers; Christine Menias; Akram Shaaban

doi:10.1016/j.rcl.2023.02.004

Malignant Germ Cell Tumors of the Ovary: Clinical and Imaging Features

Radiol Clin North Am. 2023 Jul;61(4):579-594. doi: 10.1016/j.rcl.2023.02.004. Epub 2023 Apr 3.

Authors

Douglas Rogers¹, Christine Menias², Akram Shaaban³

Affiliations

¹ Department of Radiology and Imaging Sciences, University of Utah, 30 N Medical Dr, Salt Lake City, UT 84132, USA. Electronic address: Douglas.rogers@hsc.utah.edu.
² Mayo Clinic Radiology, 13400 E Shea Boulevard, Scottsdale, AZ 85259, USA.
³ Department of Radiology and Imaging Sciences, University of Utah, 30 N Medical Dr, Salt Lake City, UT 84132, USA.

PMID: 37169425
DOI: 10.1016/j.rcl.2023.02.004

Abstract

Ovarian malignant germ cell tumors are a diverse set of masses originating from the primitive gonadal germ cells, often in young females. They have useful imaging and clinical features, including serum tumor marker elevation, that may aid the radiologist at the time of diagnosis, and also during follow-up. Accurate and timely diagnosis is essential, as standard-of-care therapies lead to a high rate of cancer remission.

Keywords: CT; Dysgerminoma; Immature teratoma; MR; Ovarian malignant germ cell tumor; Ultrasound; Yolk sac tumor.

Publication types

Review

MeSH terms

Biomarkers, Tumor
Female
Humans
Neoplasms, Germ Cell and Embryonal* / diagnostic imaging
Ovarian Neoplasms* / diagnostic imaging
Ovarian Neoplasms* / pathology

Substances

Biomarkers, Tumor