Transoral Approach to Parapharyngeal Space Tumours: Preliminary Reports from a Single-Centre Retrospective Analysis

Curr Oncol. 2023 Mar 30;30(4):3927-3939. doi: 10.3390/curroncol30040297.


Purpose: The aim of this study is to identify certain parapharyngeal space tumours with specific characteristics that can be treated successfully through an endoscopically assisted transoral approach (EATA).

Methods: Nine patients with PPS tumours underwent surgery through an EATA between 2003 and 2021. All patients underwent clinical examination and fibrolaryngoscopy. Preoperative CT and/or MRI was performed on all patients.

Results: All the patients were successfully treated through an endoscopically assisted transoral approach. Histological examination revealed five pleomorphic adenomas, two schwannomas, one ectopic thyroid gland and one lipoma. The only long-term sequelae observed was Horner syndrome in the two schwannomas arising from the carotid space. The mean hospitalisation time was 2.6 days, while the mean follow-up time was of 9.7 years.

Conclusions: An endoscopically assisted transoral approach (EATA) is a valid technique for treating benign capsulated tumours of the true PPS and some benign capsulated tumours of the superomedial aspect of the carotid space.

Keywords: benign tumours; parapharyngeal space; transoral approach.

MeSH terms

  • Adenoma, Pleomorphic* / pathology
  • Adenoma, Pleomorphic* / surgery
  • Humans
  • Neurilemmoma* / diagnostic imaging
  • Neurilemmoma* / pathology
  • Neurilemmoma* / surgery
  • Parapharyngeal Space / pathology
  • Parapharyngeal Space / surgery
  • Pharyngeal Neoplasms* / diagnostic imaging
  • Pharyngeal Neoplasms* / pathology
  • Pharyngeal Neoplasms* / surgery
  • Retrospective Studies

Grants and funding

This research received no external funding.