Although surface coating is commonly utilized in many industries for improving the aesthetics and functionality of the end product, our tactile perception of coated surfaces has not been investigated in depth yet. In fact, there are only a few studies investigating the effect of coating material on our tactile perception of extremely smooth surfaces having roughness amplitudes in the order of a few nanometers. Moreover, the current literature needs more studies linking the physical measurements performed on these surfaces to our tactile perception in order to further understand the adhesive contact mechanism leading to our percept. In this study, we first perform 2AFC experiments with 8 participants to quantify their tactile discrimination ability of 5 smooth glass surfaces coated with 3 different materials. We then measure the coefficient of friction between human finger and those 5 surfaces via a custom-made tribometer and their surface energies via Sessile drop test performed with 4 different liquids. The results of our psychophysical experiments and the physical measurements show that coating material has a strong influence on our tactile perception and human finger is capable of detecting differences in surface chemistry due to, possibly, molecular interactions.