Coded aperture snapshot spectral imaging fundus camera

Res Sq [Preprint]. 2023 May 10:rs.3.rs-2515559. doi: 10.21203/rs.3.rs-2515559/v1.

Abstract

Spectral imaging holds great promise for the non-invasive diagnosis of retinal diseases. However, to acquire a spectral datacube, conventional spectral cameras require extensive scanning, leading to a prolonged acquisition. Therefore, they are inapplicable to retinal imaging because of the rapid eye movement. To address this problem, we built a coded aperture snapshot spectral imaging fundus camera, which captures a large-sized spectral datacube in a single exposure. Moreover, to reconstruct a high-resolution image, we developed a robust deep unfolding algorithm using a state-of-the-art spectral transformer in the denoising network. We demonstrated the system performance on both standard targets and an eye phantom.

Publication types

  • Preprint