Ruptured Sinus of Valsalva Aneurysm Diagnosed on Coronary Computed Tomography Angiography in a Patient With Trisomy 13 Syndrome

Shiva Barforoshi; Chandana Sheker; Ajayram V Ullal; Venkat Manubolu; Matthew J Budoff; Sion K Roy

doi:10.14503/THIJ-22-8022

Ruptured Sinus of Valsalva Aneurysm Diagnosed on Coronary Computed Tomography Angiography in a Patient With Trisomy 13 Syndrome

Tex Heart Inst J. 2023 May 1;50(3):e228022. doi: 10.14503/THIJ-22-8022.

Authors

Shiva Barforoshi¹, Chandana Sheker², Ajayram V Ullal², Venkat Manubolu², Matthew J Budoff², Sion K Roy²

Affiliations

¹ Harbor-UCLA Medical Center, Department of Internal Medicine, Torrance, California.
² The Lundquist Institute, Cardiac CT, Division of Cardiology, Torrance, California.

Abstract

Trisomy 13 is a rare chromosomal disorder in which all or a percentage (mosaicism) of cells contain an extra 13th chromosome. Sinus of Valsalva aneurysms are rare, with an incidence of 0.1% to 3.5% of all congenital heart defects. This article reports the case of a patient with trisomy 13 with a new systolic murmur found to have a ruptured sinus of Valsalva aneurysm diagnosed on coronary computed tomography angiography. This is the first case to report sinus of Valsalva aneurysm rupture secondary to Streptococcus viridans endocarditis in a patient with trisomy 13 syndrome and highlights the importance of coronary computed tomography angiography in noninvasive imaging and surgical planning.

Keywords: Sinus of Valsalva; aneurysm; computed tomography angiography; trisomy 13 syndrome.

Publication types

Case Reports

MeSH terms

Aneurysm, Ruptured* / complications
Aortic Aneurysm* / complications
Aortic Aneurysm* / diagnostic imaging
Aortic Aneurysm* / genetics
Aortic Rupture* / etiology
Aortic Rupture* / genetics
Computed Tomography Angiography
Humans
Sinus of Valsalva* / diagnostic imaging
Sinus of Valsalva* / surgery
Trisomy 13 Syndrome / complications