ISPD Catheter-related Infection Recommendations: 2023 Update

Perit Dial Int. 2023 May;43(3):201-219. doi: 10.1177/08968608231172740. Epub 2023 May 26.


Peritoneal dialysis (PD) catheter-related infections are important risk factors for catheter loss and peritonitis. The 2023 updated recommendations have revised and clarified definitions and classifications of exit site infection and tunnel infection. A new target for the overall exit site infection rate should be no more than 0.40 episodes per year at risk. The recommendation about topical antibiotic cream or ointment to catheter exit site has been downgraded. New recommendations include clarified suggestion of exit site dressing cover and updated antibiotic treatment duration with emphasis on early clinical monitoring to ascertain duration of therapy. In addition to catheter removal and reinsertion, other catheter interventions including external cuff removal or shaving, and exit site relocation are suggested.

Keywords: Antibacterial agents; ISPD guideline; antibiotic prophylaxis; catheter-related infections; exit site infection; peritoneal dialysis; prevention; treatment outcome.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Catheter-Related Infections* / drug therapy
  • Catheter-Related Infections* / etiology
  • Catheter-Related Infections* / prevention & control
  • Catheters, Indwelling / adverse effects
  • Humans
  • Peritoneal Dialysis* / adverse effects
  • Peritonitis* / drug therapy
  • Risk Factors


  • Anti-Bacterial Agents