Admission care bundles for decompensated cirrhosis are poorly utilised across the UK: results from a multi-centre retrospective study

Clin Med (Lond). 2023 May;23(3):193-200. doi: 10.7861/clinmed.2022-0541.


Admission care bundles have been demonstrated to improve clinical outcomes for patients in several settings. Decompensated cirrhosis care bundles have been developed following previous reports demonstrating poor care for inpatients with alcohol-related liver disease (ARLD). We performed a UK multi-centred retrospective observational study to understand how frequently decompensated cirrhosis admission care bundles were utilised, who they were used for and their impact on outcomes. In this study (1,224 admissions, 104 hospitals), we demonstrated that admission care bundle usage was low across the UK (11.44%). They were more likely to be utilised in patients with ARLD or who were jaundiced, and less likely to be used in patients admitted for gastrointestinal bleeding. The admission care bundle improved the standard of alcohol care and requesting initial investigations. However, there were areas where more than 80% compliance was achieved without the use of a care bundle and areas where less than 50% compliance was achieved with the use of a care bundle. Given the low utilisation of care bundles, we were unable to demonstrate an effect on risk-adjusted mortality. Thus, interdisciplinary work is required to develop tools which are widely used and improve care and outcomes for patients with decompensated cirrhosis.

Keywords: care bundle; cirrhosis; equity; variation.

Publication types

  • Observational Study
  • Multicenter Study

MeSH terms

  • Gastrointestinal Hemorrhage
  • Hospitalization
  • Humans
  • Liver Cirrhosis / therapy
  • Patient Care Bundles*
  • Retrospective Studies
  • United Kingdom