Endoscopic Imaging of Pancreatic Cysts

Gastrointest Endosc Clin N Am. 2023 Jul;33(3):583-598. doi: 10.1016/j.giec.2023.03.005. Epub 2023 Apr 6.


Pancreatic cystic lesions (PCLs) have been diagnosed with increasing frequency likely due to the widespread use of cross-sectional imaging. A precise diagnosis of the PCL is important because it helps identify patients in need of surgical resection and those who can undergo surveillance imaging. A combination of clinical and imaging findings as well as cyst fluid markers can help classify PCLs and guide management. This review focuses on endoscopic imaging of PCLs including endoscopic and endosonographic features and fine needle aspiration. We then review the role of adjunct techniques, such as microforceps, contrast-enhanced endoscopic ultrasound, pancreatoscopy, and confocal laser endomicroscopy.

Keywords: Contrast-enhanced EUS; Endoscopic ultrasound (EUS); Intraductal papillary mucinous neoplasm (IPMN); Mucinous cystic neoplasm (MCN); Pancreatic cystic lesions; Pancreatic cystic neoplasms; Pancreatic cysts; Serous cystic neoplasm (SCN).

Publication types

  • Review

MeSH terms

  • Endoscopic Ultrasound-Guided Fine Needle Aspiration / methods
  • Endosonography / methods
  • Humans
  • Pancreas / pathology
  • Pancreatic Cyst* / diagnosis
  • Pancreatic Neoplasms* / pathology