A rare Serratia marcescens-associated acute endocarditis of a tricuspid valve in an intravenous drug user : A case report and literature review

Wien Klin Wochenschr. 2023 Nov;135(21-22):631-636. doi: 10.1007/s00508-023-02217-0. Epub 2023 May 31.

Abstract

Serratia marcescens is a gram-negative bacillus that is an opportunistic agent in respiratory tract infections, urinary tract infections, and septicemia. It is rarely also a cause of infective endocarditis which follows a rapid and devastating course, typically in persons with history of intravenous drug use (IDU). This article reports a fatal case of a 27-year-old patient with a known history of IDU, who presented with clinical symptoms concerning right-sided endocarditis as well as signs of acute respiratory distress syndrome. Finally, a detailed review of the literature is provided concerning the acute endocarditis of a tricuspid valve, especially associated with Serratia marcescens infection.

Keywords: ARDS; Drug abuse; Infective endocarditis; Serratia marcescens; Tricuspid valve.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adult
  • Drug Users*
  • Endocarditis* / complications
  • Endocarditis, Bacterial* / complications
  • Endocarditis, Bacterial* / diagnosis
  • Endocarditis, Bacterial* / drug therapy
  • Humans
  • Serratia marcescens
  • Substance Abuse, Intravenous* / complications
  • Tricuspid Valve