The role of height and weight growth in spontaneous resolution of vesicoureteral reflux

Pediatr Int. 2023 Jan-Dec;65(1):e15546. doi: 10.1111/ped.15546.


Background: The aim of this study was to investigate the role of height and weight growth in the resolution of primary vesicoureteral reflux (VUR).

Methods: We retrospectively evaluated the data of 74 males and 135 females who were diagnosed with primary VUR. According to the vesicoureteral reflux resolution, patients were divided into two groups. Patients with complete or partial resolution of VUR were included in Group 1 and patients with no resolution of VUR were included in Group 2. Patients were evaluated for weight Z-score, height Z-score and body mass index at the diagnosis and in the follow-up. In addition, age, sex, grade of reflux and laterality were recorded.

Results: There were no significant differences between the two groups, according to height Z-score, weight Z-score and body mass index at the diagnosis, in the follow-up and also annual changes of these parameters. In addition, the same parameters did not significantly differ in Groups 1 and 2, between the initial and final evaluations. However, when we evaluate the patients older than 12 months old, weight Z-scores were significantly higher at the final evaluation than at the diagnosis, in Group 1. This significant difference was not detected in Group 2 at the same age.

Conclusions: Although we could not detect the hectic pace of height growth as being important in the prediction of long-term outcomes of VUR, weight growth should be considered to predict the resolution of VUR.

Keywords: height Z-score; spontaneous resolution; vesicoureteral reflux; weight Z-score.

MeSH terms

  • Body Mass Index
  • Female
  • Humans
  • Infant
  • Male
  • Retrospective Studies
  • Vesico-Ureteral Reflux* / diagnosis