Remote neurocognitive interventions for attention-deficit/hyperactivity disorder - Opportunities and challenges

Prog Neuropsychopharmacol Biol Psychiatry. 2023 Dec 20:127:110802. doi: 10.1016/j.pnpbp.2023.110802. Epub 2023 May 29.

Abstract

Improving neurocognitive functions through remote interventions has been a promising approach to developing new treatments for attention-deficit/hyperactivity disorder (AD/HD). Remote neurocognitive interventions may address the shortcomings of the current prevailing pharmacological therapies for AD/HD, e.g., side effects and access barriers. Here we review the current options for remote neurocognitive interventions to reduce AD/HD symptoms, including cognitive training, EEG neurofeedback training, transcranial electrical stimulation, and external cranial nerve stimulation. We begin with an overview of the neurocognitive deficits in AD/HD to identify the targets for developing interventions. The role of neuroplasticity in each intervention is then highlighted due to its essential role in facilitating neuropsychological adaptations. Following this, each intervention type is discussed in terms of the critical details of the intervention protocols, the role of neuroplasticity, and the available evidence. Finally, we offer suggestions for future directions in terms of optimizing the existing intervention protocols and developing novel protocols.

Keywords: AD/HD; Cognitive training; External cranial nerve stimulation; Neurofeedback training; Neuroplasticity; Non-invasive brain stimulation; Remote intervention.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attention Deficit Disorder with Hyperactivity* / psychology
  • Electroencephalography / methods
  • Humans
  • Neurofeedback* / methods
  • Transcranial Direct Current Stimulation*