Invasive squamous cell carcinoma of the breast associated with breast augmentation implant capsule

Katherine Rosenberg; Patrick McGillen; Valentina Zanfagnin; Sandy Lee; Nafiseh Janaki; Andreea Raicu; Priya Jayachandran; Shelly Bian; Haig Yenikomshian; Stephen F Sener

doi:10.1002/jso.27364

Invasive squamous cell carcinoma of the breast associated with breast augmentation implant capsule

J Surg Oncol. 2023 Sep;128(4):495-501. doi: 10.1002/jso.27364. Epub 2023 Jun 1.

Authors

Katherine Rosenberg^{1

2}, Patrick McGillen^{2

3}, Valentina Zanfagnin^{2

4}, Sandy Lee^{1

2}, Nafiseh Janaki^{2

4}, Andreea Raicu^{2

3}, Priya Jayachandran^{2

5}, Shelly Bian^{2

6}, Haig Yenikomshian^{2

3}, Stephen F Sener^{2

3}

Affiliations

¹ Departments of Radiology, and the Norris Comprehensive Cancer Center, Keck School of Medicine of USC, University of Southern California, Los Angeles, California, USA.
² Los Angeles General Medical Center (formerly LAC), Los Angeles, California, USA.
³ Keck School of Medicine of USC, Surgery, and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
⁴ Keck School of Medicine of USC, Pathology, and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
⁵ Keck School of Medicine of USC, Medicine, and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
⁶ Keck School of Medicine of USC, Radiation Oncology, and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.

PMID: 37260104
DOI: 10.1002/jso.27364

Abstract

Primary squamous cell carcinoma (SCC) of the breast is rare, representing less than 0.1% of all breast cancers. To date, there have been 20 reported cases of SCC associated with breast augmentation, usually in patients with long-standing implants. A patient is reported here with primary squamous carcinoma of the breast associated with textured saline implants. Due to the paucity of cases, there is limited information on the incidence and management of implant-associated SCC of the breast.

Keywords: BIA-SCC; breast implant-associated squamous cell carcinoma.

Publication types

Case Reports

MeSH terms

Breast Implantation* / adverse effects
Breast Implants* / adverse effects
Breast Neoplasms* / epidemiology
Carcinoma, Squamous Cell* / complications
Carcinoma, Squamous Cell* / surgery
Female
Humans
Lymphoma, Large-Cell, Anaplastic* / etiology
Mammaplasty* / adverse effects