Candida glabrata meningitis

South Med J. 1986 Jul;79(7):916. doi: 10.1097/00007611-198607000-00037.


We have reported an unusual case of Candida glabrata meningitis causing acute changes in mental status in a chronically ill, elderly patient with non-insulin-dependent diabetes mellitus. Candida glabrata was identified by Gram stain, culture, and fermentation pattern from the CSF. Although the patient died of foreign body aspiration, an excellent clinical response was initially obtained with amphotericin B and 5-flucytosine. This is the first report of a symptomatic Candida glabrata meningitis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amphotericin B / administration & dosage
  • Candidiasis* / drug therapy
  • Chronic Disease
  • Drug Therapy, Combination
  • Female
  • Flucytosine / administration & dosage
  • Humans
  • Meningitis / drug therapy
  • Meningitis / etiology*


  • Amphotericin B
  • Flucytosine