Treating negative symptoms of schizophrenia: current approaches and future perspectives

Br J Psychiatry. 2023 Jul;223(1):332-335. doi: 10.1192/bjp.2023.57.


Negative symptoms are core symptoms of schizophrenia which are common throughout the course of the illness. We outline their functional impact, before reviewing the latest research and guidelines on their assessment and treatment. Finally, we discuss conceptual issues related to measurement of negative symptoms and approaches to address these.

Keywords: Antipsychotics; anhedonia; outcome; psychosis; trial.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antipsychotic Agents* / therapeutic use
  • Humans
  • Schizophrenia* / drug therapy
  • Schizophrenia* / therapy


  • Antipsychotic Agents