The long-term effects of the Covid-19 infection on cardiac symptoms

BMC Cardiovasc Disord. 2023 Jun 6;23(1):286. doi: 10.1186/s12872-023-03322-8.

Abstract

Background: Besides the lungs, coronavirus disease 2019 (COVID-19) can affect the cardiovascular, digestive, urinary, hepatic, and central nervous systems. Other than its short-term effects, COVID-19 may also cause long-term complications. In this study, we assessed long-term COVID-19 cardiovascular symptoms among patients in a cardiovascular clinic.

Method: A retrospective cohort was conducted between October 2020 to May 2021 on patients at an outpatient cardiovascular clinic in Shiraz, Iran. Patients with a history of COVID-19 at least one year before their referral were included. Baseline information was extracted from the clinic's database. Data were collected regarding symptoms like dyspnea, chest pain, fatigue, and palpitations after a year of COVID-19. We also noted any major adverse cardiac events (MACE).

Results: Most common symptoms after a year of COVID-19 were exertional dyspnea (51.2%), dyspnea at rest (41.6%), fatigue (39%), and chest pain (27.1%). The symptoms were more prevalent in hospitalized patients than in non-hospitalized patients. The prevalence of MACE was about 6.1% during the 12-month follow-up, with this rate being higher in those with a history of hospitalization or comorbid diseases.

Conclusion: The prevalence of cardiovascular symptoms was fairly high in patients at our clinic a year after COVID-19, and the most common symptom was dyspnea. Hospitalized patients had more MACE. (Clinicaltrial.gov number: NCT05715879)(04/02/2023).

Keywords: COVID-19; Cardiovascular system; Post-Acute COVID-19 syndrome; Signs and symptoms.

Publication types

  • Clinical Study

MeSH terms

  • COVID-19* / complications
  • COVID-19* / diagnosis
  • Chest Pain / diagnosis
  • Chest Pain / epidemiology
  • Chest Pain / etiology
  • Dyspnea / diagnosis
  • Dyspnea / epidemiology
  • Fatigue / diagnosis
  • Fatigue / epidemiology
  • Humans
  • Retrospective Studies

Associated data

  • ClinicalTrials.gov/NCT05715879