Peritoneal Carcinomatosis From Metastatic Prostate Cancer Identified on 68 Ga-Prostate-Specific Membrane Antigen PET/CT

Clin Nucl Med. 2023 Aug 1;48(8):704-706. doi: 10.1097/RLU.0000000000004734. Epub 2023 Jun 8.

Abstract

A 69-year-old man with locally advanced prostate adenocarcinoma (Gleason score 9), who had completed hormone therapy and definitive radiotherapy, presented to hospital with abdominal pain and distension. A CT scan of the abdomen and pelvis revealed ascites and extensive peritoneal/omental nodules. Serum prostate-specific antigen was not raised (0.07 μg/L). 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT demonstrated PSMA-avid disease in the prostate and widespread PSMA-avid peritoneal/omental and liver metastases but with no PSMA-avid bony metastases. Peritoneal nodule biopsy confirmed metastatic prostate cancer.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Edetic Acid
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Humans
  • Male
  • Peritoneal Neoplasms* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Prostate / pathology
  • Prostatic Neoplasms* / pathology

Substances

  • Gallium Isotopes
  • Gallium-68
  • Gallium Radioisotopes
  • Edetic Acid