Outcomes of de-prescribing proton pump inhibitors during acute admissions in a general medical unit: a pilot study

Michael T K Luc; Edward Adi-Pranoto; David Lau; Mahesan Anpalahan

doi:10.1111/imj.16123

Outcomes of de-prescribing proton pump inhibitors during acute admissions in a general medical unit: a pilot study

Intern Med J. 2023 Jun;53(6):1061-1064. doi: 10.1111/imj.16123. Epub 2023 Jun 9.

Authors

Michael T K Luc¹, Edward Adi-Pranoto¹, David Lau^{1

2}, Mahesan Anpalahan^{1

2}

Affiliations

¹ Department of General Medicine, Eastern Health, Melbourne, Victoria, Australia.
² Department of Medicine, Monash University, Melbourne, Victoria, Australia.

PMID: 37294041
DOI: 10.1111/imj.16123

Abstract

The study describes the feasibility and short-to-medium-term efficacy of an evidence-based proton pump inhibitor (PPI) de-prescribing initiative undertaken as part of routine clinical care during acute admissions in a general medical unit. Of the 44 (median (IQR) age 75.5 (13.75) years; females 25 (57%)) who participated in the study, de-prescription was maintained in 29 (66%) and 27 (61%) patients at 12 and 26 weeks respectively.

Keywords: de-prescribing; gastro-oesophageal reflux disease; proton pump inhibitors.

MeSH terms

Aged
Female
Gastroesophageal Reflux*
Hospitalization
Humans
Patients' Rooms
Pilot Projects
Proton Pump Inhibitors* / therapeutic use

Substances

Proton Pump Inhibitors