Recent Trends in Lateral Flow Immunoassays with Optical Nanoparticles

Int J Mol Sci. 2023 May 31;24(11):9600. doi: 10.3390/ijms24119600.

Abstract

Rapid, accurate, and convenient diagnosis is essential for effective disease management. Various detection methods, such as enzyme-linked immunosorbent assay, have been extensively used, with lateral flow immunoassay (LFIA) recently emerging as a major diagnostic tool. Nanoparticles (NPs) with characteristic optical properties are used as probes for LFIA, and researchers have presented various types of optical NPs with modified optical properties. Herein, we review the literature on LFIA with optical NPs for the detection of specific targets in the context of diagnostics.

Keywords: diagnosis; lateral flow immunoassay; nanoparticle; optical nanoparticles.

Publication types

  • Review

MeSH terms

  • Enzyme-Linked Immunosorbent Assay
  • Gold
  • Immunoassay / methods
  • Limit of Detection
  • Metal Nanoparticles*
  • Nanoparticles*

Substances

  • Gold