New prediction categories in CASP15

Proteins. 2023 Dec;91(12):1550-1557. doi: 10.1002/prot.26515. Epub 2023 Jun 12.

Abstract

Prediction categories in the Critical Assessment of Structure Prediction (CASP) experiments change with the need to address specific problems in structure modeling. In CASP15, four new prediction categories were introduced: RNA structure, ligand-protein complexes, accuracy of oligomeric structures and their interfaces, and ensembles of alternative conformations. This paper lists technical specifications for these categories and describes their integration in the CASP data management system.

Keywords: 3D structure prediction; CASP15; RNA structure; protein structure; protein-ligand complexes.

MeSH terms

  • Computational Biology*
  • Ligands
  • Models, Molecular
  • Protein Conformation
  • Proteins* / chemistry

Substances

  • Proteins
  • Ligands