Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun 14;13(1):9619.
doi: 10.1038/s41598-023-36100-9.

Evaluation of the antiviral activity of ultraviolet light and zinc oxide nanoparticles on textile products exposed to Avian coronavirus

David Asmat-Campos  1   2 , Jesús Rojas-Jaimes  3 , Eliana Icochea-D'Arrigo  4 , Gina R Castro-Sanguinetti  4 , Juan Anderson More-Bayona  4 , Luisa Juárez-Cortijo  5 , Daniel Delfín-Narciso  5 , Gabriela Montes de Oca-Vásquez  6
Affiliations

Evaluation of the antiviral activity of ultraviolet light and zinc oxide nanoparticles on textile products exposed to Avian coronavirus

David Asmat-Campos et al. Sci Rep. .

Abstract

This research has developed a piece of sanitizing locker-model equipment for textiles exposed to avian coronavirus, which has been put under the influence of UV light, UV + zinc oxide nanoparticles (phytosynthesized ZnONP), and water + UV, and, in turn, under the influence of the exposure time (60, 120, 180 s). The results linked to the phytosynthesis of ZnONP indicate a novel method of fabricating nanostructured material, nanoparticles with spherical morphology and an average size of 30 nm. The assays were made based on the viral viability of avian coronavirus according to the mortality of SPF embryonated eggs and a Real-Time PCR for viral load estimation. This was a model to evaluate the sanitizing effects against coronaviruses since they share a very similar structure and chemistry with SAR-CoV-2. The influence of the type of textile treatment evidenced the potential effect of the sanitizing UV light, which achieved 100% of embryo viability. The response of the ZnONP + UV nebulization showed a notorious influence of photoactivation according to the exposure time, and the 60-s treatment achieved a decrease of 88.9% in viral viability, compared to 77.8% and 55.6% corresponding to the 120 and 180-s treatments, respectively. Regarding the decrease in viral load between the types of treatments, UV 180 s reduced 98.42% and UV 60 s + ZnONP reduced 99.46%, respectively. The results show the combinatorial effect of UV light and zinc nanoparticles in decreasing the viral viability of avian coronavirus, as a model of other important coronaviruses in public health such as SARS-CoV-2.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Temporal diagram of the sanitizing locker operation process.
Figure 2
Figure 2
Characterization of ZnONPs. (a) Transmission electron microscopy shows the spherical morphology of ZnONPs with an average size of 30 nm. (b) UV vis spectrophotometry. (c) Elemental analysis by EDS.
Figure 3
Figure 3
Embryos in group 1 in which the fabric was exposed to ultraviolet light and ZnONP at 60, 120, and 180 s, and where no alterations were observed in the embryos.
Figure 4
Figure 4
Embryo alterations related to avian coronavirus infection in group 2 in which the fabric was exposed to ultraviolet light and ZnONP.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Lorusso A, Calistri P, Petrini A, Savini G, Decaro N. Novel coronavirus (SARS-CoV-2) epidemic: A veterinary perspective. Vet. Ital. 2020;56:5–10. - PubMed
    1. Gorbalenya AE, et al. The species Severe acute respiratory syndrome-related coronavirus: Classifying 2019-nCoV and naming it SARS-CoV-2. Nat. Microbiol. 2020;5:536–544. - PMC - PubMed
    1. Huang C, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. - PMC - PubMed
    1. Chu DKW, et al. Avian coronavirus in wild aquatic birds. J. Virol. 2011;85:12815–12820. - PMC - PubMed
    1. Rana A, Yadav K, Jagadevan S. A comprehensive review on green synthesis of nature-inspired metal nanoparticles: Mechanism, application and toxicity. J. Clean. Prod. 2020;272:122880.

Publication types