Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation

Li Chen; Li-Sheng Zhang; Chang Ye; Huiqing Zhou; Bei Liu; Boyang Gao; Zixin Deng; Changming Zhao; Chuan He; Bryan C Dickinson

doi:10.1038/s41422-023-00836-w

Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation

Cell Res. 2023 Sep;33(9):727-730. doi: 10.1038/s41422-023-00836-w. Epub 2023 Jun 15.

Authors

Li Chen^#^{1

2}, Li-Sheng Zhang^#^{1

3}, Chang Ye^#^{1

3}, Huiqing Zhou^{1

4}, Bei Liu^{1

3}, Boyang Gao^{3

5}, Zixin Deng², Changming Zhao⁶, Chuan He^{7

8

9}, Bryan C Dickinson¹⁰

Affiliations

¹ Department of Chemistry, The University of Chicago, Chicago, IL, USA.
² Department of Geriatrics, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei, China.
³ Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.
⁴ Chemistry Department, Boston College, Chestnut Hill, MA, USA.
⁵ Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
⁶ Department of Geriatrics, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, Hubei, China. cmzhao03@whu.edu.cn.
⁷ Department of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.
⁸ Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.
⁹ Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.
¹⁰ Department of Chemistry, The University of Chicago, Chicago, IL, USA. dickinson@uchicago.edu.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

Gene Expression Profiling* / methods
HeLa Cells
Humans
Methylation
Protein Processing, Post-Translational
Transcriptome* / genetics

Publication types

MeSH terms

Grants and funding