Celiac sprue complicated by lymphoma presenting with multiple gastric ulcers

Gastroenterology. 1986 Sep;91(3):740-5. doi: 10.1016/0016-5085(86)90648-7.


A 40-yr-old woman with celiac sprue, which had responded clinically and histologically to gluten elimination, subsequently developed gastrointestinal lymphoma. Although this has been described in the small intestine of patients with celiac sprue, the unique feature in this patient was her initial presentation with multiple gastric ulcers refractory to conventional medical therapy. This case demonstrates that lymphoma complicating celiac sprue may present with multiple refractory gastric ulcers in addition to those occurring in the small intestine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Celiac Disease / complications*
  • Celiac Disease / pathology
  • Female
  • Gastrointestinal Neoplasms / etiology*
  • Gastrointestinal Neoplasms / pathology
  • Humans
  • Jejunum / pathology
  • Lymphoma / etiology*
  • Lymphoma / pathology
  • Stomach / pathology
  • Stomach Ulcer / etiology*
  • Stomach Ulcer / pathology