CPR quality and outcomes after extracorporeal life support for pediatric In-Hospital cardiac arrest

Resuscitation. 2023 Aug:189:109874. doi: 10.1016/j.resuscitation.2023.109874. Epub 2023 Jun 14.

Abstract

Aim of study: To determine outcomes in pediatric patients who had an in-hospital cardiac arrest and subsequently received extracorporeal cardiopulmonary resuscitation (ECPR). Our secondary objective was to identify cardiopulmonary resuscitation (CPR) event characteristics and CPR quality metrics associated with survival after ECPR.

Methods: Multicenter retrospective cohort study of pediatric patients in the pediRES-Q database who received ECPR after in-hospital cardiac arrest between July 1, 2015 and June 2, 2021. Primary outcome was survival to ICU discharge. Secondary outcomes were survival to hospital discharge and favorable neurologic outcome at ICU and hospital discharge.

Results: Among 124 patients included in this study, median age was 0.9 years (IQR 0.2-5) and the majority of patients had primarily cardiac disease (92 patients, 75%). Survival to ICU discharge occurred in 61/120 (51%) patients, 36/61 (59%) of whom had favorable neurologic outcome. No demographic or clinical variables were associated with survival after ECPR.

Conclusion: In this multicenter retrospective cohort study of pediatric patients who received ECPR for IHCA we found a high rate of survival to ICU discharge with good neurologic outcome.

Keywords: Cardiac arrest; Cardiopulmonary resuscitation quality; Extracorporeal cardiopulmonary resuscitation; Paediatric intensive care unit.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cardiopulmonary Resuscitation*
  • Child
  • Extracorporeal Membrane Oxygenation*
  • Heart Arrest*
  • Hospitals
  • Humans
  • Infant
  • Retrospective Studies
  • Survival Rate
  • Treatment Outcome