Improvement in persistent idiopathic facial pain with comorbid ADHD using the combination of a dopamine system stabilizer and psychostimulant: A case report

Satoshi Kasahara; Yuichi Kato; Kaori Takahashi; Ko Matsudaira; Naoko Sato; Ken-Ichi Fukuda; Akira Toyofuku; Shin-Ichi Niwa; Kanji Uchida

doi:10.1002/ccr3.7552

Improvement in persistent idiopathic facial pain with comorbid ADHD using the combination of a dopamine system stabilizer and psychostimulant: A case report

Clin Case Rep. 2023 Jun 19;11(6):e7552. doi: 10.1002/ccr3.7552. eCollection 2023 Jun.

Authors

Satoshi Kasahara^{1

2}, Yuichi Kato³, Kaori Takahashi⁴, Ko Matsudaira², Naoko Sato⁵, Ken-Ichi Fukuda⁶, Akira Toyofuku⁷, Shin-Ichi Niwa⁸, Kanji Uchida¹

Affiliations

¹ Department of Anesthesiology and Pain Relief Center The University of Tokyo Hospital Tokyo Japan.
² Department of Pain Medicine Fukushima Medical University School of Medicine Fukushima Japan.
³ Department of Pediatric Dentistry, School of Life Dentistry at Tokyo Nippon Dental University Tokyo Japan.
⁴ Department of Dental Anesthesiology Tokyo Dental College Tokyo Japan.
⁵ Nursing Department The University of Tokyo Hospital Tokyo Japan.
⁶ Division of Special Needs Dentistry and Orofacial Pain Tokyo Dental College Tokyo Japan.
⁷ Department of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan.
⁸ Department of Psychiatry, Aizu Medical Center Fukushima Medical University Aizuwakamatsu Japan.

Abstract

Key clinical message: Persistent idiopathic facial pain (PIFP) and attention-deficit/hyperactivity disorder (ADHD) may coexist and can be improved with ADHD medications. Thus, clinicians should screen for ADHD by a multidisciplinary approach when treating PIFP and differentiate between other odontogenic disorders.

Abstract: We report a case of a woman with persistent idiopathic facial pain (PIFP) and attention-deficit/hyperactivity disorder (ADHD) that markedly improved with the administration of a combination of aripiprazole (APZ) and methylphenidate (MP) treatment. Screening for ADHD and administration of APZ and/or MP may be considered in treating PIFP.

Keywords: aripiprazole; attention‐deficit hyperactivity disorder; dopamine; methylphenidate; pain behavior; persistent idiopathic facial pain.

Publication types

Case Reports