A sound mind in a sound body: Stress-induced glucocorticoids exacerbate gut inflammation

Cell. 2023 Jun 22;186(13):2728-2730. doi: 10.1016/j.cell.2023.05.029.

Abstract

The notion that psychological stress can deteriorate our health is widely accepted. However, the mechanisms at play are poorly understood. In this issue of Cell, Schneider et al. identify the impact of glucocorticoids on enteric glia and neurons and elucidate the underlying mechanisms that link psychological stress to the exacerbation of gut inflammation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Glucocorticoids* / adverse effects
  • Humans
  • Inflammation
  • Neuroglia* / physiology
  • Neurons / physiology
  • Stress, Psychological

Substances

  • Glucocorticoids