Reactive Arthritis Following Coronavirus 2019 Infection in a Pediatric Patient: A Rare Case Report

J Hand Surg Glob Online. 2023 May 8;5(4):483-487. doi: 10.1016/j.jhsg.2023.04.012. Online ahead of print.


Reactive arthritis (ReA) following Coronavirus 2019 (COVID-19) infection has been described mainly in adults, and only two pediatric cases have been reported. We report a third case where ReA was found to be a sequela following COVID-19 infection. A 15-year-old right-handed Caucasian girl presented with severe left-wrist pain. She was experiencing fever, rash, and migratory oligoarthritis, and laboratory work-up showed elevated inflammatory markers and a positive COVID-19 IgG antibody test. Imaging revealed inflammatory arthropathy with wrist synovitis. The patient was diagnosed with ReA following COVID-19 infection and was treated surgically by wrist arthroscopic synovectomy after the failure of conservative management. It has been 1 year after her surgery, and she is doing well. Emerging case reports are linking ReA as a delayed response to COVID-19 infection; therefore, ReA should be included in the list of differential diagnoses in all patients with joint pain following COVID-19 infection.

Keywords: COVID-19; Oligoarthritis; Reactive arthritis; SARS-CoV-2; Synovitis.

Publication types

  • Case Reports