Coexistence of psoriasis and cutaneous T-cell lymphoma

Clin Exp Dermatol. 2023 Sep 19;48(10):1155-1159. doi: 10.1093/ced/llad213.

Abstract

It has been reported that individuals with psoriasis are at an increased risk of developing cutaneous T-cell lymphoma (CTCL). However, the increased risk of lymphoma in these patients has been questioned because CTCL in its early stages may be incorrectly labelled as psoriasis, thus introducing potential for misclassification bias. We retrospectively reviewed patients with a confirmed diagnosis of CTCL seen in a tertiary cutaneous lymphoma clinic (n = 115) over a 5-year period and found that 6 (5.2%) patients had clinical evidence of coexisting psoriasis. This demonstrates that there is a small cohort of individuals who develop both psoriasis and CTCL.

MeSH terms

  • Humans
  • Lymphoma, T-Cell, Cutaneous* / complications
  • Lymphoma, T-Cell, Cutaneous* / pathology
  • Psoriasis* / pathology
  • Retrospective Studies
  • Skin Neoplasms* / complications
  • Skin Neoplasms* / pathology